Core materials: why is important for pharmaceutical brand
For oral solid preparation drugs, the core material is extremely important.They help to produce high quality and stability of the drug, can enhance the solubility and change at the same time make a drug more effective drug release curve.
This guide will help you understand what is the core materials, why they are so important to pharmaceutical brand, and if you are looking for tablets or capsules of the core material solution, what are your options.
Want to know about pharmaceutical excipients solution proposal?Card nu-lax has more than 60 years of related experience, so pleaseContact us for consultation.Click here,Learn more about usThe pharmaceutical excipients product information.
What is the material?
Oral pharmaceutical excipients are active substances, can be used as a drug delivery carrier of active ingredient (API).Although the material composition is considered to be inactive part of pharmaceutical products, but they are in core plays a very important role, they can be as adhesives, lubricants and filler/thinner, also can be used as film coating to provide protection for tablets, at the same time provide color for tablet identification and branding.
Active ingredient drug tablet coating system to protect, support the stability of the product, and can be used to customize the delivery of the active ingredient.Materials do not provide any direct treatment of advantages, but they help overcome the limitations of the API: manufacturability, stability, and drug delivery.
Besides applied in medicine, auxiliary materials and applications in many places, such as dietary supplements, nutrition and animal health products.Accessories and a variety of application types, from the binder to pigment and solvent, etc.This article specifically discusses the oral solid preparation of the core material.
What is the core material?
Core material is the main drug delivery carrier.Most people focus on the active ingredients of drugs, but the core materials for the product production activity and drug treatment is very important.
The advantage of the core material
Core materials is vital in the pharmaceutical industry, there are three main advantages.
Drug absorption
Pharmaceutical excipients help drug absorption.In a liquid, for example, some of the API is not easy to dissolve, and core materials can help to improve the solubility.Another example is based on the lipid materialBy influencing the body's physiological processes to enhance the absorption of drug, such as stimulate the flow of bile and pancreatic juice secretion, etc.
Drug delivery (pharmacokinetics)
Core material of another advantage is that they can change the drug pharmacokinetic, or delivery of the drug in the body.For example, the speed of polymer can through sustained release (SR), delayed release (DR) or extended release (ER) to change the release of drugs (MR).At the same time it can also help identify specific location of drug release.
Supplementary material can ensure the drug's active ingredient reach in the right place at the right time, so as to achieve the desired effect.If a drug contains inconsistent accessories, even composition and dosage is correct, but still drug therapy may not effect.Even in some cases, may also cause harm to patients.
Drug stability
At last, the pharmaceutical excipients is helpful to improve the stability of the drug.Pharmaceutical excipients experts, card nu-lax vice-president Ali, said Dr Rajabi - Siahboomi core material to be able to:
- To prevent degradation API
- Use of antioxidants to reduce oxidative degradation
- Metal ions by chelating agent chelating induced oxidation
- In the case of material selection error promote degradation
These factors tell us why we let the correct core material is so important.
Card nu-lax accessories solution
Want to know more information?Card nu-lax can provide help for you.In more than 60 years, we have been provide core material solution for medicinal materials market.As the world's leading manufacturer of pharmaceutical excipients, we have been looking for the right materials solutions for global pharmaceutical company.
Our expert consulting the demand of the pharmaceutical company, and then use their knowledge of pharmaceutical excipients recommendation tailored solution, help to shorten development time, at the same time provide stable end product production.
Please contact usLearn more about our tablet and capsule accessories information, or visit our product page:
